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This study is currently recruiting participants.
Verified by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), April 2007

Sponsors and Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
State University of New York - Downstate Medical Center
National Institutes of Health (NIH)
Information provided by: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
ClinicalTrials.gov Identifier: NCT00458458

(A) Major 1) to compare the effectiveness of norethindrone acetate (NA) with GnRH agonist (Lupron-Depot-3) in relieving symptoms of endometriosis, 2) to compare bone density in the two treated groups in order to demonstrate that NA does not affect bone density; (B) Minor: 1) To compare the lipid profiles of patients in the two groups to confirm the hypothesis that the effects of NA and GnRH agonists on lipid profiles are similar, 2) To determine whether quality of life, assessed by questionnaire, is better in patients assigned to NA than in patients assigned to GnRH, 3) To determine whether NA has fewer adverse effects than GnRH agonist.

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News Stories

I've been asked to write "our side" of the story for terminating a pregnancy due to T-21 with known health issues. This is my story in much abbreviated form.

I was 39 when I found out I had severe endometriosis, and I underwent a laparoscopy and six months of Lupron treatment to combat it.
Shares of Neurocrine Biosciences Inc. (Nasdaq: NBIX) lifted in after-hours trading after the San Diego-based company said its endometriosis treatment proved safe and effective in its fifth Phase 2 clinical trial.
FRANKFURT -(Dow Jones)- Bayer Schering Pharma AG has successfully completed the decentralized part of drug approval procedure in Europe for a new treatment of endometriosis called Visanne, the company said Monday.
Clinical question Is laparoscopic uterosacral nerve ablation (LUNA) effective for the treatment of women with chronic pelvic pain?

Bottom line LUNA is no more effective than sham surgery in alleviating chronic pelvic pain of uncertain etiology in adult women. (Level of evidence = 1b–)

Synopsis LUNA is a therapeutic procedure performed after a diagnostic laparoscopy in women with chronic pelvic pain of uncertain etiology
Cook Medical has allowed those in the medical industry to preview its new uterine manipulator/injectors (UMI) at the recent Global Congress of Minimally Invasive Gynaecology.

The company's new UMI and UMI-Loc products are designed to improve laparoscopic procedures during the diagnosis and treatment of common gynecological problems, including infertility, pelvic organ prolapse, endometriosis and uterine fibroids.

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Polls

I have tried Lupron and ...
it didnt work
it didnt work and had side effects
it worked well
it worked but with side effects
i have not tried it ever
Have you tried Zoladex and did it work?
Never used it 66 % 66%
Used it and it worked 9 % 9%
Used it and it didnt work 14 % 14%
Unsure 8 % 8%
I've had Endometriosis and so has...
My Sister 12 % 12%
My Mother 17 % 17%
My Daughter 0%
My Grandmother 8 % 8%
My Auntie 12 % 12%
My Cousin 11 % 11%
None 36 % 36%
Other 1 % 1%
I have Endometriosis and..
I have never smoked 65 % 65%
I used to smoke 14 % 14%
I smoke 20 % 20%
I have Endometriosis and..
I have never been pregnant 52 % 52%
I have been pregnant before but had a termination. 8 % 8%
I have been pregnant before but had a miscarrage 12 % 12%
I have 1 child 10 % 10%
I have 2 or more children. 12 % 12%
I have children but have had complications. 3 % 3%